Month: July 2023

We’re bombarded with advertisements that tout all sorts of health benefits for vitamins and supplements, including improved memory. A May 2023 study of older adults suggests that a daily multivitamin can do just that — improve your memory enough such that it can function as if you were three years younger.

So, should you take that daily multivitamin? Let’s take a close look at the study.

Who took part in this multivitamin study?

This research is part of a larger study examining the effects of a multivitamin and/or cocoa (the main ingredient in chocolate) on cardiovascular and cancer outcomes. A prior sub-study found that a daily multivitamin improved thinking and memory — at least when evaluated with cognitive testing completed by phone.

For this study, 3,562 participants were willing and able to perform some tests of thinking and memory on a home computer. Half received a multivitamin; the other half received a placebo.

The participants identified as 93% white, 2.5% African American, and 1.4% Hispanic, so the results may not be generalizable. They were also well educated: more than half had completed college. In both groups, the average age was 71.

How did the researchers test memory?

The investigators evaluated the participants’ thinking and memory at baseline and after one, two, and three years.

For the memory test, participants were asked to memorize 20 words shown consecutively on a computer screen. Immediately after viewing these words, they had to type in as many words as they could remember (this was the primary measure of memory). Fifteen minutes later, they also typed in all the words they recalled (a secondary measure of memory).

Other secondary measures included:

• a novel object discrimination test (is this object the same or different from one recently shown?)
• an executive control test (in an array of nine arrows, is the central arrow red or blue?).

The participants repeated all of the tests one, two, and three years later.

What were the results of this study?

The two groups differed in immediate recall at year one:

• Those who took a placebo went from immediately recalling an average of 7.21 words at baseline to 7.65 words (a difference of 0.43 words)
• Those who took a daily multivitamin group went from 7.10 words at baseline to 7.81 words (a difference of 0.70 words).

This result was statistically significant. Additionally, these small effects held up at years two and three. By year three, the placebo group immediately recalled an average of 8.17 words and the multivitamin group immediately recalled 8.28 words.

No differences occurred between the two groups on secondary memory and executive function tests.

How can a multivitamin improve memory?

The authors note that low levels of vitamins B12 and D have been linked to cognitive decline and dementia. In a subset of participants who had their blood drawn, the levels of these vitamins did rise in the multivitamin group.

It seems plausible that a few of the 3,562 participants had low levels of these or other vitamins that are important for thinking and memory. In the placebo group, the few who had vitamin deficiencies would likely show less improvement in memory after their baseline tests, or a small decline. By contrast, those few participants in the multivitamin group with deficiencies would have them corrected by the supplements and, therefore, would perform relatively better.

Although this is just speculation, it would explain the small but seemingly real results — results that replicate the researchers' prior study, which used a telephone cognitive test to show thinking and memory benefit from a daily multivitamin.

It’s also worth noting that practice on memory tasks — the so-called practice effect — could contribute to small improvements shown from baseline to year one and year three.

Should you take a multivitamin to improve your memory?

The authors admitted that the effect of the multivitamin on immediate memory was small and may not be noticeable. However, they pointed out that this small effect could be important at the level of an entire population.

My opinion? You shouldn’t bother taking a multivitamin to try to improve your immediate recall of 20 words from 8.17 to 8.28 words. But it is worth speaking with your doctor about whether you could have a vitamin deficiency in B1, B6, B12, D, or any other important vitamins. I see several patients in my clinic every week who have startlingly low levels of vitamin D and B12. Your doctor may want to measure these levels. Or they may suggest simply taking a multivitamin daily.

If, after reading this article, you’ve decided to take a multivitamin, please check with your doctor or pharmacist about which one would be best for you. Make sure that they review any other vitamins, supplements, and medications you take to avoid rare but serious interactions.

About the Author

Andrew E. Budson, MD, Contributor; Editorial Advisory Board Member, Harvard Health Publishing

Dr. Andrew E. Budson is chief of cognitive & behavioral neurology at the Veterans Affairs Boston Healthcare System, lecturer in neurology at Harvard Medical School, and chair of the Science of Learning Innovation Group at the … See Full Bio View all posts by Andrew E. Budson, MD

There are certain things our bodies do so often and so automatically that we barely notice them. Yawning, growling stomachs, and runny noses are good examples. Each is a universal part of our daily human experience.

But did you ever wonder why? Below are a few things we know and a few we suspect.

Why do you yawn?

Perhaps you associate yawning only with being tired or bored. While we don’t know exactly why people yawn, there’s no shortage of theories. Yawning may

• stretch out our lungs and nearby tissues, preventing tiny airways in the lungs from collapsing
• distribute a chemical called surfactant, a gooey liquid that coats the tiny air pockets in the lungs and helps keep them open
• help prepare our bodies for transitions between wakefulness and rest: For example, yawning often occurs after a period of relaxation and when awakening from sleep. And it may serve as an internal signal that it’s time to sleep, or time to take a break from activities (such as driving).
• play a role in maintaining proper brain temperature: Our brain functions best within a narrow range of temperatures. Some experts believe yawning can help cool the brain through complex effects on nearby circulation and the sinuses.

It’s also unclear why yawning is contagious. In the animal kingdom, it’s common to see contagious yawning among members of a group, perhaps as a signal for collective behavior (such as moving from activity to rest).

Why does your stomach growl?

That rumbling in your stomach is known medically as borborygmi — an excellent Scrabble word if you have the right letters. We usually assume it reflects hunger. And it’s true that the experience of hunger can make itself heard in anticipation of a meal.

But your stomach may also growl after a meal, when the stomach and intestines propel liquids and food through the digestive tract. Stress can also trigger stomach rumbling.

What’s causing all that noise — and is it ever a problem? It may be due to gas moving around in response to muscular contractions of the intestinal walls. Occasionally, noises from the abdomen may be a sign of an intestinal infection or other trouble. If you’re experiencing other symptoms, such as pain or fever, check in with your doctor. But the vast majority of noises are harmless and a sign that your gut is working normally.

Why does your nose run?

Sometimes it can seem like your nose is running for no reason. But there are some well-known triggers, such as:

• Infection. When you have a cold, mucous membranes produce more mucus as part of your defense system: more mucous flowing out means fewer germs getting in.
• Allergies. Pollen, ragweed, or other triggers stimulate immune cells that produce histamine. Histamine opens up blood vessels just beneath the mucous membranes, and that leads to increased production and release of fluid and mucus. As with infection, this response may be helpful to dilute the offending trigger and rid it from the area.
• Cold, dry air. The inside surface of the nose is covered with mucous membranes that warm and humidify air well before it reaches the lungs. When you inhale dry, cold air through your nose, these membranes humidify the air by secreting water and mucus.
• Spicy foods. Spices like capsaicin act as an irritant to the sinuses and mucous membranes, which release fluid in response.

The bottom line

Some of the most common everyday human experiences are also some of the least understood. There are many other examples, of course: Why are we ticklish? What purpose do hiccups serve? What’s the deal with brain freeze? Perhaps topics for another day.

It may seem like a leap of faith, but it’s likely there are very good reasons for the way our bodies work — even when we don’t know what those reasons are.

About the Author

Robert H. Shmerling, MD, Senior Faculty Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing

Dr. Robert H. Shmerling is the former clinical chief of the division of rheumatology at Beth Israel Deaconess Medical Center (BIDMC), and is a current member of the corresponding faculty in medicine at Harvard Medical School. … See Full Bio View all posts by Robert H. Shmerling, MD

Busy days make it hard to put heart health on the front burner. It just feels like you don't have time for habits that keep the ticker in top shape — like exercising regularly, getting enough sleep, and eating a healthy diet. So maybe you take the stairs when you can, or you park farther away from a store to rack up a few extra steps each day. But what else can you do? Here are three things that might fit in your schedule.

Swap electronic communication for an in-person meeting

It's fine if texting, emailing, social media, or Zoom calls are your primary means of communicating with others. But it's not okay if those methods leave you feeling lonely or isolated — two problems linked to higher risks for heart disease, heart attack, or stroke, according to a scientific statement from the American Heart Association in the Journal of the American Heart Association.

To combat loneliness and isolation, try to replace some of your electronic back-and-forth with people with in-person meetings. Maybe you can find room in your schedule for a quick walk, cup of coffee, or brief lunch with a friend or colleague.

"Time spent face-to-face helps connect you to others and may make you feel less isolated," explains Matthew Lee, a sociologist and research associate at Harvard University's Human Flourishing Program. "Being physically co-present can help you feel more engaged with others, more valued, and more likely to feel a sense of shared identity — all things that may help ease loneliness. This is why some doctors are starting to engage in 'social prescribing,' including suggesting that people get involved in volunteering and other activities that build in-person social relationships."

A recent study published in the International Journal of Public Health by Lee and a team of Harvard-led researchers suggests that better social connectedness may reduce the risk of being diagnosed with depression or anxiety. Both are associated with heart disease or making existing heart conditions worse.

Swap an unhealthy breakfast for a healthier one

Is your typical breakfast something quick and full of refined (not whole) grains, processed meat, saturated fat, or added sugar? Eating that kind of food regularly may drive up calories, weight, blood sugar, or cholesterol levels — and that's not good for your heart.

Instead, choose breakfast foods rich in fiber, a type of carbohydrate that either passes through the body undigested (insoluble fiber) or dissolves into a gel (soluble fiber) that coats the gut.

Not only does fiber help digestion, it also

• traps, mops up, and lowers bad [LDL] cholesterol that can lead to clogged arteries
• controls blood sugar and lowers the risk for diabetes, which is strongly associated with heart attacks and strokes
• may help fight chronic inflammation, which plays a role in clogging arteries and causing heart attacks.

Fruits, nuts, seeds, whole grains (oats, barley, quinoa) and many other foods are rich in fiber. Try these fiber-rich breakfast ideas:

• microwaved oatmeal (heat a 1/2 cup of oatmeal with almost a cup of low-fat milk for about two minutes)
• a serving of cooked quinoa (cold, if you have it in your fridge) with a dollop of nonfat Greek yogurt, berries, and granola
• whole-grain cereal with milk (go for cereals with the highest amounts of whole grains and lowest amounts of added sugars)
• a slice of whole-grain toast with two tablespoons of nut butter (like almond or peanut butter)
• one or two handfuls of homemade trail mix (use your favorite unsalted nuts, sunflower seeds, and dried fruit such as raisins or apricots).

Swap a few minutes of scroll time for meditation time

If you ever take a break from your busy day to scroll through news on your phone or computer, chances are you can also find a little time to meditate, which is important for heart health. Research indicates that people who meditate have lower rates of high cholesterol, diabetes, high blood pressure, stroke, and coronary artery disease compared with people who don't meditate.

What's the connection? Meditating triggers the body's relaxation response, a well-studied physiological change that appears to help lower your blood pressure, heart rate, breathing rate, oxygen consumption, adrenaline levels, and levels of the stress hormone cortisol.

The great news: it doesn't take much time to reap the heart-healthy benefits of meditating — just about 10 to 20 minutes per day.

Ideas for quick ways to meditate in a busy day include sitting quietly, closing your eyes, and

• focusing on your breathing, without judging sounds you hear or thoughts that pop into your head
• listening to a guided meditation, which uses mental images to help you relax
• listening to a recording of calming sounds such as waves, a bubbling brook, or gentle rain.

Just try to calm your brain for a few minutes a day. Soon, you may find you've become better at meditating and better at practicing other heart-healthy habits, no matter how busy you are.

About the Author

Heidi Godman, Executive Editor, Harvard Health Letter

Heidi Godman is the executive editor of the Harvard Health Letter. Before coming to the Health Letter, she was an award-winning television news anchor and medical reporter for 25 years. Heidi was named a journalism fellow … See Full Bio View all posts by Heidi Godman